Genitourinary Pathology Services


Aurora Diagnostics Biopsy Diagnostics offers high-quality, customer service-oriented urologic pathology services. Every biopsy and cytology specimen is microscopically examined to render a reliable and accurate diagnosis. Moreover, our pathologists employ a variety of sophisticated diagnostic techniques, including special stains, IHC, and molecular testing, to ensure the precision of each diagnosis and to assist the referring physician in the selection of the most appropriate patient treatment option.

Urologic Pathology Service Highlights:

Our Expertise
  • Board-certified pathologists with experience and expertise in urologic pathology
  • Accurate and definitive diagnoses reported; correlation of histology sections with DNA ploidy studies,
    immunophenotyping, and special stains, as required
  • In-house consultations by multiple, board-certified pathologists with subspecialty expertise in GI pathology
  • Participation in quality assurance programs
  • Laboratory accreditation by the College of American Pathologists

Comprehensive Test Menu

  • Histology and cytology services
  • Immunohistochemical and special stains are available to diagnose a wide range of neoplastic and infectious diseases.
  • Advanced Molecular Diagnostics
    o FISH
    o Tumor markers

Prostate Histology
  • All prostate biopsies are extensively studied with serial sections on multiple separate levels, resulting in 8-to-12
    sections examined on each biopsy core.
  • Diagnostic report incorporating digital photography, diagrammatic representation of prostate gland, and
    color-coded diagnoses.
  • Immunohistochemical specialty stains, such as high-molecular weight cytokeratin, p63, and p504s
    (alpha-methylacyl-CoA racemase) for a definitive diagnosis in the evaluation of borderline lesions of minute foci of
    prostatic adenocarcinoma.
  • In-house consultation by multiple board-certified pathologists with over 40 years of expertise in urologic pathology.

Urine Cytology
  • Routine Cytologic evaluation with collection kits provided.
  • Detection and Monitoring of Recurrent Bladder Cancer
    o UroVysion™ FISH performed by specialists in FISH technology (In combination with routine cytology the multicolor
       FISH probes provide the most sensitive and specific methodology for monitoring of recurrent bladder cancer.)
       For more information
  • Stone analysis

UroVysionTM FISH Testing
  • UroVysionTM FISH Testing has been FDA approved as screen for recurrent bladder cancer, increasing the sensitivity
    from 58% with routine cytology alone to 98% when used in combination with cytology and cystoscopy.
  • This molecular test utilizes fluorescence in situ hybridization (FISH) to test abnormalities in four different
    chromosomes linked to urothelial carcinomas. The use of FISH in conjuction with urine cytology can potentially reduce
    urothelial carcinoma morbidity and mortality by diagnosing these tumors earlier. UroVysionTM is not affected
    by: BCG therapy, infections, BPH or hematuria.
  • This molecular test utilizes fluorescence in situ hybridization (FISH) to test abnormalities in four different
    chromosomes linked to urothelial carcinomas. The use of FISH in conjunction with urine cytology can potentially
    reduce urothelial carcinoma morbidity and mortality by diagnosing these tumors earlier. UroVysionTM is not affected
    by: BCG therapy, infections, BPH or hematuria.
  • UroVysionTM and routine cytology can both be performed on the same specimen. Simply pour the urine into the
    UroVysionTM Fish collection container and add an equal volume of the provided fixative. Order on the requisition
    "CYTOLOGY & VROVYSION FISH". Then place the bar code label marked "UroVysion" on the container. The test
    may be performed on voided urine or bladder washing specimens.
  • There is no need to send us two separate specimens. We will split the specimen for you.